A generalized global alignment algorithm

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A generalized global alignment algorithm

MOTIVATION Homologous sequences are sometimes similar over some regions but different over other regions. Homologous sequences have a much lower global similarity if the different regions are much longer than the similar regions. RESULTS We present a generalized global alignment algorithm for comparing sequences with intermittent similarities, an ordered list of similar regions separated by d...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2003

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/19.2.228